Biologically Active Peptides

[Biologically active peptides].

Handbook of Biologically Active Peptides

Pheromones are chemical messages known to elicit changes in behavioral reactions that are followed by physiological alterations in conspecific receiver organisms. Pheromones comprise a wide range of compounds, of varied chemical nature, that range from small-molecule volatile compounds to high-molecular-weight, water-soluble, nonvolatile peptides and proteins. Although volatile pheromone molecu...

Biologically active peptides in milk proteins.

Bioactive peptides have been identified as digestion products of several food proteins. All the bioactive sequences are hidden in an inactive state inside the polypeptide chain of the larger protein. Milk proteins are a rich source of biologically active peptides such as exorphins (casomorphins), phosphopeptides and immunopeptides. Such peptides are released during intestinal digestion of casei...

Biologically active peptides: prospects for drug development

Biologically active peptides are typified by their ubiquity of distribution, their high receptor affinity and an almost infinite diversity of structure. For these reasons, considerable effort is now being expended to elucidate the possible role of peptides in brain function. This effort has been stimulated by the discovery of a number of new endogenous peptides, such as the enkephalins, endorph...

The renal handling of biologically active peptides.

With the use of the protease inhibitor from bovine organs--Trasylol-- as a model, we studied the pinocytic transport of peptides in the kidney. Rats were injected with the 125I-labeled peptide and killed at different times thereafter. Kidney homogenates were subfractionated by differential and sucrose gradient centrifugation. Radioactivity was measured in the fractions in order to study the tim...